Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 12 Reviews
8.6
Supplement Facts
Serving Size: 1 Level Teaspoon (approx. 2 g)
Serving Per Container:  About 85
Amount Per Serving
%DV
Calories
10
 
Total Carbohydrate
2 g
<1%*
Total Sugars 
2 g
†
Organic D-Mannose
2 g (2,000 mg)
†

Top Medical Research Studies

We explored a new targeted agent designed to treat atherosclerosis by focusing on macrophage-mannose receptors. This study tested the effectiveness and safety of a specially formulated nanoagent in a mouse model of atherosclerosis.

The agent showed a notable reduction in inflammation within the arterial plaques while being well-tolerated in terms of toxicity. We found it had good imaging capabilities, allowing for better visualization of macrophages linked to atherosclerosis.

Overall, this promising approach may improve both the diagnosis and treatment of cardiovascular diseases linked to atherosclerosis.
Read More
7
Mannose linked to heart risks
We explored how mannose levels relate to insulin resistance and cardiovascular health in a large group of participants. By analyzing data from 1,403 individuals, including those who suffered a heart attack, we found that high mannose was linked to increased risks of adverse cardiac events, regardless of glucose levels and traditional risk factors.

This suggests that mannose could serve as a novel marker to detect harmful changes in metabolic health that could lead to cardiovascular issues down the line. However, it is essential to note that this study highlights association rather than a direct cause-and-effect relationship.
Read More

Most Useful Reviews

9
Chronic cystitis beaten
15 people found this helpful
D-Mannose has been life-changing for me! This simple saccharide binds E. coli in the bladder, preventing outbreaks of cystitis. I take three capsules at the first signs of an attack, stopping the bacterial growth effectively. After ceasing hormonal pills—previously taken for over a year—I was relieved not to face another bout of cystitis after three months. My experience has positively transformed my life, and I hope my review encourages others to try it!
Read More
9
Inflammation managed effectively
13 people found this helpful
Mannose has resolved my sister's chronic inflammation problems. While conventional medicine only offered symptomatic relief, Mannose effectively confronted the underlying issues right at the onset. My sister's mood and health have improved significantly since using it. I wholeheartedly endorse Mannose for anyone battling similar symptoms—it is both effective and lasting.
Read More
9
Cystitis episodes diminished
8 people found this helpful
D-mannose has become essential for my kidney health. It's a tasteless powder that I mix with water. Following three years of daily use, my cystitis occurrences have dropped to nearly none. Following just a couple of doses during an inflammatory phase brings me relief. Given its natural composition, I cannot recommend it highly enough!
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
  • All Researches
We explored a new targeted agent designed to treat atherosclerosis by focusing on macrophage-mannose receptors. This study tested the effectiveness and safety of a specially formulated nanoagent in a mouse model of atherosclerosis.

The agent showed a notable reduction in inflammation within the arterial plaques while being well-tolerated in terms of toxicity. We found it had good imaging capabilities, allowing for better visualization of macrophages linked to atherosclerosis.

Overall, this promising approach may improve both the diagnosis and treatment of cardiovascular diseases linked to atherosclerosis.
Read More
7
Mannose linked to heart risks
We explored how mannose levels relate to insulin resistance and cardiovascular health in a large group of participants. By analyzing data from 1,403 individuals, including those who suffered a heart attack, we found that high mannose was linked to increased risks of adverse cardiac events, regardless of glucose levels and traditional risk factors.

This suggests that mannose could serve as a novel marker to detect harmful changes in metabolic health that could lead to cardiovascular issues down the line. However, it is essential to note that this study highlights association rather than a direct cause-and-effect relationship.
Read More

User Reviews

USERS' SCORE
Good
Based on 12 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Chronic cystitis beaten
15 people found this helpful
D-Mannose has been life-changing for me! This simple saccharide binds E. coli in the bladder, preventing outbreaks of cystitis. I take three capsules at the first signs of an attack, stopping the bacterial growth effectively. After ceasing hormonal pills—previously taken for over a year—I was relieved not to face another bout of cystitis after three months. My experience has positively transformed my life, and I hope my review encourages others to try it!
Read More
9
Inflammation managed effectively
13 people found this helpful
Mannose has resolved my sister's chronic inflammation problems. While conventional medicine only offered symptomatic relief, Mannose effectively confronted the underlying issues right at the onset. My sister's mood and health have improved significantly since using it. I wholeheartedly endorse Mannose for anyone battling similar symptoms—it is both effective and lasting.
Read More
9
Cystitis episodes diminished
8 people found this helpful
D-mannose has become essential for my kidney health. It's a tasteless powder that I mix with water. Following three years of daily use, my cystitis occurrences have dropped to nearly none. Following just a couple of doses during an inflammatory phase brings me relief. Given its natural composition, I cannot recommend it highly enough!
Read More
9
Antibiotic-free
1 people found this helpful
I have struggled with chronic UTIs for nearly 40 years. After repeated antibiotic courses, I was introduced to d-mannose by an infectious diseases specialist. It worked like magic, stopping my UTIs and easing my chronic thrush. Now, I use it preventatively or at the first signs of symptoms, rarely needing antibiotics. What relief!
Read More
10
Highly effective
A brilliant remedy against cystitis; I recommend it 1,000,000%! It helped me eradicate the disease effectively.
Read More

Frequently Asked Questions

9
Chronic cystitis beaten
15 people found this helpful
D-Mannose has been life-changing for me! This simple saccharide binds E. coli in the bladder, preventing outbreaks of cystitis. I take three capsules at the first signs of an attack, stopping the bacterial growth effectively. After ceasing hormonal pills—previously taken for over a year—I was relieved not to face another bout of cystitis after three months. My experience has positively transformed my life, and I hope my review encourages others to try it!
9
Inflammation managed effectively
13 people found this helpful
Mannose has resolved my sister's chronic inflammation problems. While conventional medicine only offered symptomatic relief, Mannose effectively confronted the underlying issues right at the onset. My sister's mood and health have improved significantly since using it. I wholeheartedly endorse Mannose for anyone battling similar symptoms—it is both effective and lasting.
7.5
Relapse prevention
1 people found this helpful
I bought this supplement for my wife, who frequently suffers from cystitis. While I cannot judge its effectiveness entirely, it appears to have significantly contributed to her avoiding antibiotics for months. Previously, she needed treatment every 1-2 months due to relapses.
7.5
Cystitis relief
2 people found this helpful
Thanks to mannose, I have been free from cystitis recurrence for half a year. It alleviates the severity of acute cystitis, allowing it to pass in a milder form and enabling quick treatment. I take half a teaspoon daily, and at the first signs, I double the dose. Stay well!
9
Improved symptoms
2 people found this helpful
For those suffering from cystitis, this is a true godsend. I bought it for a friend who was desperate. Initially, I didn’t believe in mannose, but decided to give it a try. Remarkably, just a few days later, she felt better. After the course, I completely forgot about the disease. We also incorporated cranberries into her regimen.
7.5
Effective prevention
2 people found this helpful
I have long suffered from urinary bladder and kidney diseases, including frequent postcoital cystitis. After trying various medications, I discovered my salvation: I take d-mannose and cranberry extract. This regime truly works for me.
We explored a new targeted agent designed to treat atherosclerosis by focusing on macrophage-mannose receptors. This study tested the effectiveness and safety of a specially formulated nanoagent in a mouse model of atherosclerosis.

The agent showed a notable reduction in inflammation within the arterial plaques while being well-tolerated in terms of toxicity. We found it had good imaging capabilities, allowing for better visualization of macrophages linked to atherosclerosis.

Overall, this promising approach may improve both the diagnosis and treatment of cardiovascular diseases linked to atherosclerosis.
7
Mannose linked to heart risks
We explored how mannose levels relate to insulin resistance and cardiovascular health in a large group of participants. By analyzing data from 1,403 individuals, including those who suffered a heart attack, we found that high mannose was linked to increased risks of adverse cardiac events, regardless of glucose levels and traditional risk factors.

This suggests that mannose could serve as a novel marker to detect harmful changes in metabolic health that could lead to cardiovascular issues down the line. However, it is essential to note that this study highlights association rather than a direct cause-and-effect relationship.

References

  1. Lee SY, Kim JH, Song JW, Min JS, Kim HJ, et al. Macrophage-mannose-receptor-targeted photoactivatable agent for in vivo imaging and treatment of atherosclerosis. Int J Pharm. 2024;654:123951. doi:10.1016/j.ijpharm.2024.123951
  2. Fortin E, Campi B, Ferrannini E, Mari A, Mellbin LG, et al. High Mannose Correlates With Surrogate Indexes of Insulin Resistance and Is Associated With an Increased Risk of Cardiovascular Events Independently of Glycemic Status and Traditional Risk Factors. Diabetes Care. 2024;47:246. doi:10.2337/dc23-0870
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